diff --git a/erpnext/regional/india/e_invoice/utils.py b/erpnext/regional/india/e_invoice/utils.py
index b4e7a8889e..0315c83fd1 100644
--- a/erpnext/regional/india/e_invoice/utils.py
+++ b/erpnext/regional/india/e_invoice/utils.py
@@ -43,8 +43,9 @@ def validate_eligibility(doc):
 	invalid_supply_type = doc.get('gst_category') not in ['Registered Regular', 'SEZ', 'Overseas', 'Deemed Export']
 	company_transaction = doc.get('billing_address_gstin') == doc.get('company_gstin')
 	no_taxes_applied = not doc.get('taxes')
+	has_non_gst_item = any(d for d in doc.get('items') if frappe.db.get_value('Item', d.get('item_code'), 'is_non_gst'))
 
-	if invalid_company or invalid_supply_type or company_transaction or no_taxes_applied:
+	if invalid_company or invalid_supply_type or company_transaction or no_taxes_applied or has_non_gst_item:
 		return False
 
 	return True