diff --git a/erpnext/assets/doctype/asset/asset.py b/erpnext/assets/doctype/asset/asset.py
index 252a3dd63f..04ec7be3cd 100644
--- a/erpnext/assets/doctype/asset/asset.py
+++ b/erpnext/assets/doctype/asset/asset.py
@@ -148,17 +148,33 @@ class Asset(AccountsController):
 			frappe.throw(_("Item {0} must be a non-stock item").format(self.item_code))
 
 	def validate_cost_center(self):
-		if not self.cost_center:
-			return
-
-		cost_center_company = frappe.db.get_value("Cost Center", self.cost_center, "company")
-		if cost_center_company != self.company:
-			frappe.throw(
-				_("Selected Cost Center {} doesn't belongs to {}").format(
-					frappe.bold(self.cost_center), frappe.bold(self.company)
-				),
-				title=_("Invalid Cost Center"),
+		if self.cost_center:
+			cost_center_company, cost_center_is_group = frappe.db.get_value(
+				"Cost Center", self.cost_center, ["company", "is_group"]
 			)
+			if cost_center_company != self.company:
+				frappe.throw(
+					_("Cost Center {} doesn't belong to Company {}").format(
+						frappe.bold(self.cost_center), frappe.bold(self.company)
+					),
+					title=_("Invalid Cost Center"),
+				)
+			if cost_center_is_group:
+				frappe.throw(
+					_(
+						"Cost Center {} is a group cost center and group cost centers cannot be used in transactions"
+					).format(frappe.bold(self.cost_center)),
+					title=_("Invalid Cost Center"),
+				)
+
+		else:
+			if not frappe.get_cached_value("Company", self.company, "depreciation_cost_center"):
+				frappe.throw(
+					_(
+						"Please set a Cost Center for the Asset or set an Asset Depreciation Cost Center for the Company {}"
+					).format(frappe.bold(self.company)),
+					title=_("Missing Cost Center"),
+				)
 
 	def validate_in_use_date(self):
 		if not self.available_for_use_date: