diff --git a/erpnext/accounts/doctype/payment_entry/payment_entry.py b/erpnext/accounts/doctype/payment_entry/payment_entry.py
index 7257e6d75f..a3a7be2958 100644
--- a/erpnext/accounts/doctype/payment_entry/payment_entry.py
+++ b/erpnext/accounts/doctype/payment_entry/payment_entry.py
@@ -346,6 +346,12 @@ class PaymentEntry(AccountsController):
 								)
 							)
 
+						if ref_doc.doctype == "Purchase Invoice" and ref_doc.get("on_hold"):
+							frappe.throw(
+								_("{0} {1} is on hold").format(d.reference_doctype, d.reference_name),
+								title=_("Invalid Invoice"),
+							)
+
 					if ref_doc.docstatus != 1:
 						frappe.throw(_("{0} {1} must be submitted").format(d.reference_doctype, d.reference_name))
 
diff --git a/erpnext/accounts/doctype/payment_entry/test_payment_entry.py b/erpnext/accounts/doctype/payment_entry/test_payment_entry.py
index 5b70b510d2..a8211c81f1 100644
--- a/erpnext/accounts/doctype/payment_entry/test_payment_entry.py
+++ b/erpnext/accounts/doctype/payment_entry/test_payment_entry.py
@@ -743,6 +743,21 @@ class TestPaymentEntry(unittest.TestCase):
 			flt(payment_entry.total_taxes_and_charges, 2), flt(10 / payment_entry.target_exchange_rate, 2)
 		)
 
+	def test_payment_entry_against_onhold_purchase_invoice(self):
+		pi = make_purchase_invoice()
+
+		pe = get_payment_entry("Purchase Invoice", pi.name, bank_account="_Test Bank USD - _TC")
+		pe.reference_no = "1"
+		pe.reference_date = "2016-01-01"
+
+		# block invoice after creating payment entry
+		# since `get_payment_entry` will not attach blocked invoice to payment
+		pi.block_invoice()
+		with self.assertRaises(frappe.ValidationError) as err:
+			pe.save()
+
+		self.assertTrue("is on hold" in str(err.exception).lower())
+
 
 def create_payment_entry(**args):
 	payment_entry = frappe.new_doc("Payment Entry")
diff --git a/erpnext/accounts/doctype/sales_invoice/test_sales_invoice.py b/erpnext/accounts/doctype/sales_invoice/test_sales_invoice.py
index a0c0eccff1..b8154dd1f9 100644
--- a/erpnext/accounts/doctype/sales_invoice/test_sales_invoice.py
+++ b/erpnext/accounts/doctype/sales_invoice/test_sales_invoice.py
@@ -3140,6 +3140,39 @@ class TestSalesInvoice(unittest.TestCase):
 		si.reload()
 		self.assertTrue(si.items[0].serial_no)
 
+	def test_sales_invoice_with_disabled_account(self):
+		try:
+			account = frappe.get_doc("Account", "VAT 5% - _TC")
+			account.disabled = 1
+			account.save()
+
+			si = create_sales_invoice(do_not_save=True)
+			si.posting_date = add_days(getdate(), 1)
+			si.taxes = []
+
+			si.append(
+				"taxes",
+				{
+					"charge_type": "On Net Total",
+					"account_head": "VAT 5% - _TC",
+					"cost_center": "Main - _TC",
+					"description": "VAT @ 5.0",
+					"rate": 9,
+				},
+			)
+			si.save()
+
+			with self.assertRaises(frappe.ValidationError) as err:
+				si.submit()
+
+			self.assertTrue(
+				"Cannot create accounting entries against disabled accounts" in str(err.exception)
+			)
+
+		finally:
+			account.disabled = 0
+			account.save()
+
 	def test_gain_loss_with_advance_entry(self):
 		from erpnext.accounts.doctype.journal_entry.test_journal_entry import make_journal_entry
 
diff --git a/erpnext/accounts/general_ledger.py b/erpnext/accounts/general_ledger.py
index 89034ebb8c..1598d914e2 100644
--- a/erpnext/accounts/general_ledger.py
+++ b/erpnext/accounts/general_ledger.py
@@ -31,6 +31,7 @@ def make_gl_entries(
 	if gl_map:
 		if not cancel:
 			validate_accounting_period(gl_map)
+			validate_disabled_accounts(gl_map)
 			gl_map = process_gl_map(gl_map, merge_entries)
 			if gl_map and len(gl_map) > 1:
 				save_entries(gl_map, adv_adj, update_outstanding, from_repost)
@@ -45,6 +46,26 @@ def make_gl_entries(
 			make_reverse_gl_entries(gl_map, adv_adj=adv_adj, update_outstanding=update_outstanding)
 
 
+def validate_disabled_accounts(gl_map):
+	accounts = [d.account for d in gl_map if d.account]
+
+	Account = frappe.qb.DocType("Account")
+
+	disabled_accounts = (
+		frappe.qb.from_(Account)
+		.where(Account.name.isin(accounts) & Account.disabled == 1)
+		.select(Account.name, Account.disabled)
+	).run(as_dict=True)
+
+	if disabled_accounts:
+		account_list = "<br>"
+		account_list += ", ".join([frappe.bold(d.name) for d in disabled_accounts])
+		frappe.throw(
+			_("Cannot create accounting entries against disabled accounts: {0}").format(account_list),
+			title=_("Disabled Account Selected"),
+		)
+
+
 def validate_accounting_period(gl_map):
 	accounting_periods = frappe.db.sql(
 		""" SELECT
diff --git a/erpnext/controllers/queries.py b/erpnext/controllers/queries.py
index abe9977c84..eeb5a7f1a9 100644
--- a/erpnext/controllers/queries.py
+++ b/erpnext/controllers/queries.py
@@ -162,6 +162,7 @@ def tax_account_query(doctype, txt, searchfield, start, page_len, filters):
 				{account_type_condition}
 				AND is_group = 0
 				AND company = %(company)s
+				AND disabled = %(disabled)s
 				AND (account_currency = %(currency)s or ifnull(account_currency, '') = '')
 				AND `{searchfield}` LIKE %(txt)s
 				{mcond}
@@ -175,6 +176,7 @@ def tax_account_query(doctype, txt, searchfield, start, page_len, filters):
 			dict(
 				account_types=filters.get("account_type"),
 				company=filters.get("company"),
+				disabled=filters.get("disabled", 0),
 				currency=company_currency,
 				txt="%{}%".format(txt),
 				offset=start,
diff --git a/erpnext/public/js/controllers/accounts.js b/erpnext/public/js/controllers/accounts.js
index 84c717676c..c1fe72bb48 100644
--- a/erpnext/public/js/controllers/accounts.js
+++ b/erpnext/public/js/controllers/accounts.js
@@ -27,7 +27,8 @@ frappe.ui.form.on(cur_frm.doctype, {
 					query: "erpnext.controllers.queries.tax_account_query",
 					filters: {
 						"account_type": account_type,
-						"company": doc.company
+						"company": doc.company,
+						"disabled": 0
 					}
 				}
 			});