Items like machinery, furniture, land and property, patents etc. can be categorized as fixed asset of a company. In ERPNext, you can maintain fixed asset items, mainly stock items in a separate Warehouse.
If your asset item is serialized, click [here]({{docs_base_url}}/user/videos/learn/serialized-inventory.html) to learn how serialized inventory is managed in ERPNext.
Separate Warehouse should be created for the fixed asset items. All the sales, purchase and stock transactions for asset items should be done for fixed asset warehouse only.
As per the perpetual inventory valuation system, accounting ledger is auto-created for a warehouse. You can move the accounting ledger of fixed asset asset from Stock Asset (default group) to Fixed Asset's group account.